How sulfate polysaccharides prevents the replication of virus.

Hello everyone:
        Today we will see about some of the interesting facts about viral infection and action of sulfate polysaccharides. 


Sulfate polysaccharides:
      Mostly it is derived from marine algae, seaweeds etc. These marine derived polysaccharides have the ability to inhibit the replication of virus inside the host cells. 

First of all.. We want to know about the life cycle of virus. 

How virus attacks the host cell? 

                Attachment to the host cell
              
          Penetration into the host cell

      Releasing virions ( uncoating) 
    
   Biosynthesis ( replication) 

    These are the various stages of virus infection in host. Sulfate polysaccharides have the ability to inhibits virus multiplication in different life stages. 

During attachment:
         The enveloped virus have positive charges around the cell. The host cells are negatively charged. So these interactions will make  easier attachment for virus. When, sulfate polysaccharides present in the host cell then it increases the density of negative charge on cell. If virus will attached with host cell then the sulfate polysaccharides penetrates and disrupt the viral structure and prevents attachment. 

During penetration:
            After attachment to the host cell, virus gets penetrates into the host cell       ( interaction between positive and negatively charged cells) .The sulfated polysaccharides blocks the viral penetration into the host cell. They also prevents its attachment on host cell surface. 

Uncoating:
            After viral penetration, it enters into intracellular fluid ( cytoplasm) of the cell. It will get attached by the host protein and it will produce specific signals around the host endosome.After that it releases the virions by removing the cell coating. 
           In presence of sulfate polysaccharides, it prevents release of virions by interfere with the virus cell. It inhibits the viral replication. 

Inhibits viral replication:
            Finally the sulfate polysaccharides interacts with protein molecules and transcripting enzymes of virus and prevents it's action. 

      These are the important functions of sulfate polysaccharides on the replication of virus into host cell. 

       Next topic is about important natural feed supplement in shrimp farming which contains sulfate polysaccharides. 

     For more info and aquaculture technical support.... Pls contact.. Share and subscribe. 

Thanks and regards, 

P. Dhivagar BFSc, 
dhivagarfcri2000@gmail.com

Comments

Post a Comment

Popular posts from this blog

Better clarification about pH and Alkalinity in shrimp pond. Water quality series -3

Image
  Hello everyone:     Most of us confused between pH and alkalinity in the pond ecosystem. If there is low concentration of pH and alkalinity means we can increase but if there is high pH and alkalinity means it is some difficult to reduce .           pH and Alkalinity are related but different. pH and Alkalinity:       If you have shrimp pond then you definitely know the variance of pH in the water. You want to know means , you can check 4 to 5 times in a day. you must saw the pH fluctuations. Yes, pH is very important factor determines the shrimp culture. based on the level of pH you can tell , what happening in your shrimp pond.       Fluctuations of pH is mainly determined by amount of carbon dioxide in your pond water. Other factors like soil pH, soil deposits like calcium carbonate, planktons density also determines the changes of pH in your water.   pH :       I am also tell the same meaning, pH is determined by hydrogen ion concentration.             pH low - high hydrogen
Read more >>>

How copepods develops in shrimp pond after applying fermented juice?

Image
Hello everyone:      Are you know which is shrimp favourite food in zooplanktons? Yes, it is copepods. Shrimp eats more copepods which is present in the pond.       In last blog, I told about the reactions and preparation of fermented juice using organic substrates. It is the continuation of that blog. In this I will tell about how zooplanktons(especially copepods) developed after fermented juice application. Main purpose of fermented juice in shrimp pond:      Increase the beneficial microbial colonies by fermentation and produce various substances which is beneficial for beneficial organism growth. After application, it will forms the microbial proteins in the water column. It serve as a natural food for shrimp at stocking time.     Initially, we have to give some natural live feeds because it increases the strength and natural immune system of the Shrimp. So only we prepared for development of zooplanktons in the pond.   What are planktons?         Phytoplankton and Zoo
Read more >>>

How temperature plays major role in shrimp farming.(Water quality series - 1)

Image
Hello everyone:      Today we will see the importance of temperature in shrimp culture. What are the problems will come due to the temperature variance in shrimp pond.      Most of the persons who doing shrimp farm must know about the things what happened during temperature Change.       Shrimp grows very fastly, but we can't culture throughout the year. Why?     If you are doing intensive or super intensive system means no problem. But you are doing the culture of shrimp on outside means you have to fix the culture days based on climate change(keep in mind). Ok let's jump into topic. Temperature :       Most of the farmers doing in outer earthern pond. So in these situations, temperature plays important role in growth of our shrimp. We all focus only on ammonia, nitrite, H2S, but indirectly temperature plays very crucial role.         Heat is produced in water due to sunlight. Because sunlight have some energy in the form of photons , when it comes to contact with
Read more >>>